Notices

Notice of Proposed Rule
64-4.208 MMTC Background Screening(opens in new tab)
This rulemaking amends Rule 64-4.208 F.A.C., to update incorporated material, definitions, timeframes, and language requiring submission of background screening information to the Department.
This rule outlines the process and form necessary for required background screening of medical marijuana treatment center employees, owners, and managers to implement section 381.986, Florida Statutes.
Published in Vol. 52 No. 185, 9/23/2026

Notice of Proposed Rule
64-4.214 MMTC Application for MMTC Licensure(opens in new tab)
Pursuant to Chapter 2025-199, § 15, Laws of Florida, this rulemaking initiates nonemergency rulemaking to replace emergency rule 64ER22-9, adopted by the Department to implement section 381.986, Florida Statutes.
This rule sets forth requirements applicable to medical marijuana treatment centers (MMTCs) when applying for MMTC licensure.
Published in Vol. 52 No. 177, 9/11/2026

Notice of Proposed Rule
64-4.227 MMTC Advertising and Marketing(opens in new tab)
This rulemaking initiates nonemergency rulemaking pursuant to Chapter 2025-199, § 15, Laws of Florida, to replace Emergency Rule 64ER25-6, adopted by the Department to implement section 381.986, Florida Statutes.
This rule implements standards for advertising and marketing by medical marijuana treatment centers (MMTCs).
Published in Vol. 52 No. 164, 8/24/2026

Notice of Correction
64-4.303 CMTL Testing(opens in new tab)
64-4.306 CMTL Testing Methods(opens in new tab)
64-4.307 CMTL Submission for Product Testing(opens in new tab)
64-4.309 CMTL Quality Control Samples(opens in new tab)
Notice is hereby given that the following correction has been made to the proposed rule in Vol. 51 No. 84, April 30, 2025, issue of the Florida Administrative Register.
Published in Vol. 52 No. 159, 8/17/2026

Notice of Change
64-4.218 MMTC Trade Name and Logo (opens in new tab)
Notice is hereby given that the following changes have been made to the proposed rule in accordance with subparagraph 120.54(3)(d)1., F.S., published in Vol. 52 No. 93, May 13, 2026, issue of the Florida Administrative Register.
Published in Vol. 52 No. 155, 8/11/2026

Notice of Change
64-4.215 Renewal Application Requirements for MMTCs(opens in new tab)
Notice is hereby given that the following changes have been made to the proposed rule in accordance with subparagraph 120.54(3)(d)1., F.S., published in Vol. 52 No. 90, May 8, 2026, issue of the Florida Administrative Register.
Published in Vol. 52 No. 152, 8/6/2026

Notice of Withdrawal
64-4.002 Initial Application Requirements for Dispensing Organizations(opens in new tab)
64-4.004 Revocation of Dispensing Organization Approval(opens in new tab)
64-4.005 Inspection and Authorization Procedures(opens in new tab)
Notice is hereby given that the above rules, as noticed in Vol. 52 No. 63, April 1, 2026, issue of the Florida Administrative Register have been withdrawn.
Published in Vol. 52 No. 139, 7/20/2026

Notice of Rule Development
64-4.227 MMTC Advertising and Marketing(opens in new tab)
This rulemaking implements standards for advertising and marketing by medical marijuana treatment centers (MMTCs).
Published in Vol. 52 No. 111, 6/9/2026

Notice of Proposed Rule
64-4.209 MMTC Solvent-Based Extraction(opens in new tab)
Pursuant to Chapter 2025-199, § 15, Laws of Florida, this rulemaking initiates nonemergency rulemaking to replace emergency rule 64ER21-13, adopted by the Department to implement section 381.986, Florida Statutes.
This rule sets forth requirements applicable to medical marijuana treatment centers (MMTCs) when processing marijuana using hydrocarbon solvents or other solvents or gases exhibiting potential toxicity to humans.
Published in Vol.52 No.105, 6/1/2026

Notice of Proposed Rule
64-4.205 Standards for Production of Edibles(opens in new tab)
64-4.218 MMTC Trade Name and Logo(opens in new tab)
64-4.219 MMTC Packaging and Labeling(opens in new tab)
This rulemaking initiates nonemergency rulemaking pursuant to Chapter 2025-199, § 15, Laws of Florida, to replace emergency rules 64ER20-32, 64ER20-35, and 64ER22-2 adopted by the Department to implement section 381.986, Florida Statutes.
These rules set forth the requirements for medical marijuana treatment centers (MMTCs) standards for production of edibles, trade name and logo, and packaging, and labeling
Published in Vol.52 No.93, 5/13/2026

Notice of Proposed Rule
64-4.215 Renewal Application Requirements for MMTCs(opens in new tab)
64-4.217 MMTC Financial Assurance(opens in new tab)
64-4.221 MMTC Seed-to-Sale Tracking System Integration(opens in new tab)
64-4.222 MMTC STS Tracking System Procedures(opens in new tab)
64-4.224 Dosing and Supply Limits for Medical Marijuana(opens in new tab)
This rulemaking initiates nonemergency rulemaking to replace the emergency rules 64ER25-1, 64ER22-1, 64ER24-1, 64ER24-2, and 64ER22-8 adopted by the Department to implement section 381.986, Florida Statutes, pursuant to Chapter 2025-199, § 15, Laws of Florida.
SUMMARY: These rules set forth requirements for medical marijuana treatment centers (MMTCs) for licensure renewal, financial assurance, the MMTC Seed-to-Sale Tracking System, and dosing limits.
Published in Vol. 52 No. 90, 5/8/2026

Notice of Proposed Rule
64-4.002 Initial Application Requirements for Dispensing Organizations(opens in new tab)
64-4.004 Revocation of Dispensing Organization Approval(opens in new tab)
64-4.005 Inspection and Authorization Procedures(opens in new tab)
Rules 64-4.002, 4.004, and 4.005, F.A.C., address initial application requirements for dispensing organizations, revocation of dispensing organization approval, and inspection and authorization procedures for dispensing organizations, respectively. Rules 64-4.002, 4.004, and 4.005, F.A.C., will be repealed due to unnecessary and duplicative language.
Published in Vol. 52 No. 63, 4/1/2026

Notice of Rule Development
64-4.225 MMTC Marijuana Delivery Devices(opens in new tab)
64-4.226 MMTC Harvest Failures and Wholesale Transfers(opens in new tab)
This rulemaking initiates nonemergency rulemaking to replace the emergency rules 64ER25-4 and 64ER25-5 pursuant to Chapter 2025-199, § 15, Laws of Florida, adopted by the Department to implement sections 381.986, Florida Statutes.
Published in Vol. 52 No. 62, 3/31/2026

Notice of Rule Development
64-4.011 Medical Marijuana Use Registry Identification Cards(opens in new tab)
To make amendments to Rule 64-4.011, F.A.C. pursuant to chapter 2025-204, Laws of Florida, to update the Medical Marijuana Use Registry (MMUR) identification card process, incorporated forms, and requirements for patients and caregivers.
Published in Vol. 52 No. 62, 3/31/2026

Notice of Withdrawal
64-4.011 Medical Marijuana Use Registry Identification Cards(opens in new tab)
Notice is hereby given that the above rule, as noticed in Vol. 51 No. 156, August 12, 2025, issue of the Florida Administrative Register has been withdrawn.
Published in Vol. 52 No. 61, 3/30/2026

Notice of Proposed Rule
64-4.216 MMTC Authorization Procedures(opens in new tab)
64-4.223 Caregiver Background Screening and Request for Close Relative Status(opens in new tab)
Pursuant to Ch. 2025-199, § 15, Laws of Florida, this rulemaking initiates nonemergency rulemaking to replace emergency rules 64ER21-10 and 64ER23-2, adopted by the Department to implement section 381.986, Florida Statutes. These rules set forth MMTC authorization procedures, background screenings for caregivers who are not identified as close relatives, and a process to substantiate close relative of a qualified patient status.
Published in Vol. 52 No. 38, 2/25/2026

Notice of Emergency Rule
64ER25-5 MMTC Marijuana Delivery Devices(opens in new tab)
New rulemaking is required to establish an approval process for delivery devices through the submission of a variance from a MMTC. The rule includes requirements for recall of devices deemed unsafe and packaging requirements for devices for consistent with existing packaging and labeling requirements for usable products.
Published in Vol. 51 No. 248, 12/24/2025

Notice of Emergency Rule
64ER25-4 MMTC Harvest Failures and Wholesale Transfers(opens in new tab)
New rulemaking is required to establish an approval process for a medical marijuana treatment center to make a wholesale purchase of marijuana from, or a distribution of marijuana to, another medical marijuana treatment center to include submitting proof of harvest failure to the department.
Published in Vol. 51 No. 248, 12/24/2025

Notice of Development of Rulemaking
64-4.001 Definitions(opens in new tab)
64-4.205 Standards for Production of Edibles(opens in new tab)
64-4.209 MMTC Solvent-Based Extraction(opens in new tab)
64-4.214 Application for MMTC Licensure(opens in new tab)
64-4.215 Renewal Application Requirements for MMTCs(opens in new tab)
64-4.216 MMTC Authorization Procedures(opens in new tab)
64-4.217 MMTC Financial Assurance(opens in new tab)
64-4.218 MMTC Trade Name and Logo(opens in new tab)
64-4.219 MMTC Packaging and Labeling(opens in new tab)
64-4.220 MMTC Website and Website Purchasing(opens in new tab)
64-4.221 MMTC Seed-to-Sale Tracking System Integration(opens in new tab)
64-4.222 MMTC STS Tracking System Procedures(opens in new tab)
64-4.223 Caregiver Background Screening and Request for Close Relative Status(opens in new tab)
64-4.224 Dosing and Supply Limits for Medical Marijuana(opens in new tab)
This rulemaking initiates nonemergency rulemaking to replace the emergency rules (64ER20-31, 64ER20-32, 64ER20-35, 64ER21-10, 64ER21-13, 64ER22-1, 64ER22-2, 64ER22-7, 64ER22-8, 64ER22-9, 64ER23-2, 64ER24-1, 64ER24-2, 64ER25-1) adopted by the Department to implement sections 381.986, Florida Statutes, pursuant to Chapter 2025-199, § 14, Laws of Florida.
Published in Vol. 51 No. 169, 8/29/2025

Notice of Rule Development
64-4.208 MMTC Background Screening(opens in new tab)
The Department proposes to amend rule 64-4.208 to update incorporated material, and clarify terms, timeframes, and language requiring submission of information to the Department pursuant to Chapter 2025-114, Laws of Florida.
Published in Vol. 51 No. 148, 7/31/2025

Notice of Rule Development
64-4.206 Low-THC and Medical Marijuana Packaging and Labeling(opens in new tab)
This rule will establish the packaging and labeling requirements for low-THC cannabis and medical marijuana products dispensed by medical marijuana treatment centers.
Published in Vol. 48 No. 92, 5/11/2022

Notice of Proposed Rule
64-4.013 Pesticide Use on Medical Marijuana(opens in new tab)
64-4.207 MMTC Marijuana Waste Management and Disposal(opens in new tab)
64-4.212 MMTC Regulatory Compliance Testing(opens in new tab)
64-4.213 MMTC Remediation(opens in new tab)
This rulemaking amends the current rule language for Rule 64-4.013, F.A.C., and initiates nonemergency rulemaking to replace the emergency rules (64ER19-3, 64ER20-16, 64ER20-36, and 64ER20-37) adopted by the Department to implement section 381.986, Florida Statutes.
Published in Vol. 47 No. 171, 9/2/2021

Notice of Rule Development
64-4.013 Pesticide Use on Medical Marijuana(opens in new tab)
This rulemaking initiates nonemergency rulemaking to replace emergency rule (64ER19-3) which amended Rule 64-4.013, F.A.C., to add to existing requirements for certain pesticides registered with the U.S. EPA. The new requirements include that the pesticide product label must expressly have directions for use on unspecified crops or unspecified plants, must expressly have directions for use on crops or plants intended for human consumption, and the active ingredient(s) in such pesticide are allowed for use on tobacco by the U.S. EPA.
Published in Vol. 47 No. 2, 1/5/2021

Notice of Rule Development
64-4.207 Marijuana Waste Management and Disposal (opens in new tab)
This rulemaking initiates nonemergency rulemaking to replace the emergency rule (64ER20-16) adopted by the Department to implement section 381.986(8)(e)11.c., F.S., by establishing procedures for the storage, handling, transportation, management, and disposal of solid and liquid waste generated during marijuana production and processing by medical marijuana treatment centers.
Published in Vol. 47 No. 2, 1/5/2021

Notice of Rule Development
64-4.212 MMTC Regulatory Compliance Testing (opens in new tab)
This rulemaking initiates nonemergency rulemaking to replace the emergency rule (64ER20-36) adopted by the Department to implement section 381.986, Florida Statutes. Rule 64-4.212, F.A.C., establishes procedures for regulatory compliance testing of Final Products, including requirements for resampling and retesting of Retail Batches that fail regulatory compliance testing.
Published in Vol. 47 No. 2, 1/5/2021

Notice of Rule Development
64-4.213 MMTC Remediation (opens in new tab)
This rulemaking initiates nonemergency rulemaking to replace the emergency rule (64ER20-36) adopted by the Department to implement section 381.986, Florida Statutes. Rule 64-4.213, F.A.C., establishes procedures for an MMTC to remediate a Retail Batch that initially fails regulatory compliance testing.
Published in Vol. 47 No. 2, 1/5/2021

Notice of Change
64-4.210 MMTC Fines, Suspension, and Revocation(opens in new tab)
Published in Vol. 46 No. 72, 4/13/2020

Notice of Change
64-4.208 MMTC Background Screening(opens in new tab)
Published in Vol. 46 No. 72, 4/13/2020

Notice of Change
64-4.202 MMTC Inspection Procedures(opens in new tab)
Published in Vol. 46 No. 72, 4/13/2020

Notice of Rule Development
64-4.001 Definitions(opens in new tab)
To update the existing definitions rule related to medical marijuana treatment centers in order to add and update definitions necessary for additional rules being promulgated at this time.
Published in Vol. 45 No. 238, 12/10/2019

Notice of Rule Development
64-4.201 Renewal Application Requirements for MMTCs(opens in new tab)
This rule establishes the requirements for renewal of medical marijuana treatment center licenses. The rule adopts the renewal form and instructions.
Published in Vol. 45 No. 239, 12/11/2019

Notice of Rule Development
64-4.202 MMTC Inspection Procedures(opens in new tab)
The purpose of this rule is to set forth the procedures for inspections of medical marijuana treatment centers (MMTCs) as set forth in section 381.986(10), FS. The effect is to apprise MMTCs of the requirements related to inspections and the procedures to be followed.
Published in Vol. 45 No. 238, 12/10/2019

Notice of Rule Development
64-4.207 Marijuana Waste Management and Disposal(opens in new tab)
This rule is intended to dictate the manner in which marijuana waste must be managed and disposed of by licensed medical marijuana treatment centers (MMTCs) in order to protect public health and prevent against diversion.
Published in Vol. 45 No. 238, 12/10/2019

Notice of Rule Development
64-4.208 MMTC Background Screening(opens in new tab)
This rule is intended to outline the process and form necessary for required background screening of medical marijuana treatment center employees, owners, and managers as required by section 381.986, FS.
Published in Vol. 45 No. 238, 12/10/2019

Notice of Rule Development
64-4.209 Low-THC and Medical Marijuana Solvent Based Extraction and Related Products(opens in new tab)
This rule implements s. 381.986(8)(e)11.b., Florida Statutes, to establish the criteria under which medical marijuana treatment centers may process low-THC cannabis and medical marijuana using hydrocarbon solvents or other solvents or gases exhibiting potential toxicity to humans.
Published in Vol. 45 No. 239, 12/11/2019

Notice of Rule Development
64-4.210 MMTC Fines, Suspension, and Revocation(opens in new tab)
This purpose of this rule is to set forth guidelines related to fines, license suspension, and license revocation imposed upon medical marijuana treatment centers (MMTCs) for violations of rule and statute. The effect is to establish comprehensive and consistent disciplinary penalties related to MMTCs.
Published in Vol. 45 No. 238, 12/10/2019

Notice of Rule Development
64-4.211 Supplemental Licensure Fee for MMTCs(opens in new tab)
This rule will establish the supplemental licensure fee required by s. 381.986(8)(b), F.S., and the process required for submittal of the fee.
Published in Vol. 45 No. 239, 12/11/2019

Notice of Proposed Rule
64-4.013 Pesticide Use on Medical Marijuana(opens in new tab)
To amend existing rule language to conform with updated Department of Agriculture and Consumer Services recommendations regarding which certain pesticides may be legally used on marijuana by approved medical marijuana treatment centers and to make technical changes.
Published in Vol. 44 No. 223, 11/15/2018

Notice of Change
64-4.018 Medical Marijuana Treatment Center Change of Ownership Application(opens in new tab)
This rule implements s. 381.986(8)(e)1., Florida Statutes, by establishing a procedure for the Florida Department of Health to process ownership transfer requests made by a medical marijuana treatment center.
Published in Vol. 44 No. 221, 11/13/2018

Notice of Change
64-4.023 Medical Marijuana Treatment Center Variance Procedure(opens in new tab)
This rule implements s. 381.986(8)(e), F.S., by establishing a procedure for the Florida Department of Health to grant variances from the representations made in a medical marijuana treatment center’s initial application for registration.
Published in Vol. 44 No. 221, 11/13/2018

Notice of Proposed Rule
64-4.027 Pigford Class Application for Registration of Medical Marijuana Treatment Center (opens in new tab)
This rulemaking provides a process and application for those qualified individuals or entities under section 381.986(8)(a)2.b., Florida Statutes to apply for registration as a medical marijuana treatment center.
Published in Vol. 44 No. 183, 9/19/2018

Notice of Rule Development
64-4.025 Medical Marijuana Treatment Center Supplemental Licensing Fee(opens in new tab)
To create a new rule to establish supplemental licensure fees in accordance with the provisions of section 381.986(8)(b), Florida Statutes.
Published in Vol. 44 No. 170, 8/30/2018

Notice of Rule Development
64-4.015 Dosing for Low-THC Cannabis and Medical Marijuana (opens in new tab)
The Department of Health announces the convening of a negotiated rulemaking proceeding to address daily dose amounts and equivalent dose amounts for each allowable form of marijuana dispensed by a medical marijuana treatment center. The purpose of the negotiated rulemaking is to draft a mutually acceptable proposed rule.
Published in Vol. 44 No. 155, 8/9/2018

Notice of Proposed Rule
64-4.026 Application for Registration of Pigford Class and Additional Medical Marijuana Treatment Centers(opens in new tab)
This rulemaking provides a process and application for those qualified individuals or entities under section 381.986(8)(a)2.b., Florida Statutes and those who wish to apply pursuant to section 381.986(8)(a)4., Florida Statutes, to apply for registration as a medical marijuana treatment center.
Published in Vol. 44 No. 155, 8/9/2018

Notice of Change
64-4.002 Application for Registration of Medical Marijuana Treatment Centers(opens in new tab)
These rules implement statutory changes to section 381.986, Florida Statutes, to update definitions and processes for the registration of medical marijuana treatment centers.
Published in Vol. 44 No. 137, 7/16/2018

Notice of Rule Development
64-4.004 Revocation of Dispensing Organization Approval(opens in new tab)
To update and amend existing language based upon changes in law.
Published in Vol. 44 No. 76, 4/18/2018

Notice of Rule Development
64-4.005 Inspection and Authorization Procedures(opens in new tab)
To update and amend existing language based upon changes in law.
Published in Vol. 44 No. 76, 4/18/2018

Notice of Rule Development
64-4.016 Testing Lab Certification and Testing Standards(opens in new tab)
This rule will establish a procedure for laboratory certification, establish the standards for certification of marijuana testing laboratories and minimum laboratory standards.
Published in Vol. 44 No. 23, 2/2/2018

Notice of Rule Development
64-4.017 Medical Marijuana Treatment Center Dispensing Facility Allocation(opens in new tab)
This rule implements s. 381.986(8)(a)5., Florida Statutes, by setting the number of regional dispensing facilities each medical marijuana treatment center may establish and operate.
Published in Vol. 44 No. 23, 2/2/2018

Notice of Rule Development
64-4.019 Medical Marijuana Treatment Center Personnel and Caregiver Background Screenings(opens in new tab)
This rule will establish the procedure for background screenings for medical marijuana treatment center owners, officers, board members, managers, employees, and for patient caregivers.
Published in Vol 44 No. 23, 2/2/2018

Notice of Rule Development
64-4.020 Low-THC and Medical Marijuana Packaging and Labeling(opens in new tab)
This rule will establish the packaging and labeling requirements for low-THC cannabis and medical marijuana products.
Published in Vol. 44 No. 23, 2/2/2018

Notice of Rule Development
64-4.021 Low-THC and Medical Marijuana Solvent Based Extraction and Related Products(opens in new tab)
This rule implements s. 381.986(8)(e)10.b., Florida Statutes, to establish the criteria under which medical marijuana treatment centers may process low-THC cannabis and medical marijuana using hydrocarbon solvents or other solvents or gases exhibiting potential toxicity to humans.
Published in Vol. 44 No. 23, 2/2/2018

Notice of Rule Development
4.022 Marijuana Treatment Center Advertising and Signage(opens in new tab)
This rule implements s. 381.986(8)(h), Florida Statutes, to establish the criteria under which medical marijuana treatment centers may engage in advertising and marketing.
Published in Vol. 44 No. 23, 2/2/2018

Notice of Rule Development
64-4.024 Medical Marijuana Treatment Center Waste Management(opens in new tab)
This rule implements s. 381.986(8)(e)10.c., Florida Statutes, to establish procedures for the storage, handling, transportation management, and disposal of solid and liquid waste generated during low-THC and medical marijuana production and processing.
Published in Vol. 44 No. 23, 2/2/2018

Notice of Rule Development
64-4.014 Standards for Production of Edibles(opens in new tab)
This rule implements s. 381.986(8)(e)8., Florida Statutes, to establish the criteria under which medical marijuana treatment centers may produce edible products. Under section 120.54(7)(a), Florida Statutes, this rule development is responsive to the Petition to Initiate Rulemaking received by the Department of Health on September 29, 2017.
Published in Vol. 43 No. 210, 10/30/2017